RHOFADE® (oxymetazoline hydrochloride) for the treatment of ongoing facial redness due to rosacea in adults.

RHOFADE cream is a prescription medicine used on the skin (topical) to treat ongoing facial redness due to rosacea in adults.

INDICATIONS AND USAGE
Rhofade® (oxymetazoline hydrochloride, 1%) cream is an alpha1A adrenoceptor agonist indicated for the topical treatment of persistent facial erythema associated with rosacea in adults.

IMPORTANT SAFETY INFORMATION

WARNINGS AND PRECAUTIONS

  • Alpha-adrenergic agonists as a class may impact blood pressure. Advise patients with cardiovascular disease, orthostatic hypotension, and/or uncontrolled hypertension or hypotension to seek medical care if their condition worsens.
  • Use with caution in patients with cerebral or coronary insufficiency, Raynaud’s phenomenon, thromboangiitis obliterans, scleroderma, or Sjögren’s syndrome and advise patients to seek medical care if signs and symptoms of potentiation of vascular insufficiency develop.
  • Advise patients to seek immediate medical care if signs and symptoms of acute narrow-angle glaucoma develop.

ADVERSE REACTIONS
Most common adverse reactions (incidence ≥ 1%) are application site dermatitis, worsening inflammatory lesions of rosacea, application site pruritis, application site erythema, and application site pain.

MEDICAL INFORMATION and ADVERSE DRUG EVENTS REPORTING
To report a suspected adverse reaction from one of our products, please contact Mayne Pharma at 1-844-825-8500 or the FDA at 1-800 FDA-1088 or www.fda.gov/medwatch.

For more information, please see full Prescribing Information and Patient Information Leaflet.

REVISED 9/23.